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  • Managing Long COVID: A Comprehensive Guide

Blog

10 Aug

Managing Long COVID: A Comprehensive Guide

  • By Martin McPhilimey
  • In Blog, Breathing
Long Covid Rehab

Managing Long COVID: A Comprehensive Guide

In the wake of the COVID-19 pandemic, the medical community has been battling with a new challenge: Long COVID. Despite the virus being relatively new, significant strides have been made in understanding and managing its long-term effects. This blog post offers an in-depth look into the pathology of and rehab involved in managing Long COVID, the impact on our body systems, and potential rehabilitation strategies.

What is Long COVID?

Long COVID, or post-COVID syndrome, refers to a range of symptoms that persist for weeks or months after the acute phase of a COVID-19 infection has resolved. According to the NICE guidelines in the UK, Long COVID is a condition where symptoms persist for more than two to three months, with no other diagnosis to explain these long-term symptoms.

Understanding the Virus’s Impact

How Viruses Work

Viruses, COVID-19 included, function by invading human cells and hijacking cellular machinery to replicate themselves. The COVID-19 virus, with its notorious spike protein, attaches to ACE2 receptors on cells, particularly in the lungs, allowing it to enter and initiate the cycle of infection and replication. This process not only damages the infected cell but also triggers an intense immune response.

COVID-19 and Long-term Inflammation

The excessive immune response, often called a cytokine storm, creates significant inflammation. This inflammation affects different body systems, particularly the lungs where it can lead to pneumonia and restrictive lung disease. Over time, the inflammation often persists, causing scarring and long-term dysfunction.

Symptoms of Long COVID

The most common symptoms of Long COVID include fatigue, shortness of breath, myalgia (muscle pain), joint pain, sleep disturbances, and cognitive impairments like anxiety and memory problems. These symptoms mirror those found in chronic fatigue syndrome and other post-viral syndrome.

Pathophysiology of Long COVID

Research has suggested that Long COVID could be considered a multi-systemic inflammatory disorder, affecting the cardiopulmonary, metabolic, and even neurological systems. Pathologically, pulmonary fibrosis, thrombus, and bleeding are more common in influenza patients than in COVID-19 patients. However, long term dysfunction is more prevalent in COVID most likely due to the indirect impacts of bed rest, inactivity during the lock downs and the additional psychological stressors associated with a global pandemic. Commonly seen issues include:

1. Dysfunctional Breathing: Often due to abnormal ventilatory responses.

2. Deconditioning: Muscle atrophy and decreased physical fitness.

3. Mitochondrial Dysfunction: Impaired energy production at the cellular level.

4. Autonomic Nervous System Dysfunction: Problems such as POTS (Postural Orthostatic Tachycardia Syndrome).

5. Inflammatory Responses: Persistent inflammation in various tissues, including the vascular system and brain.

Rehabilitation Strategies for Managing Long COVID

Rehabilitation from Long COVID is a multi-phased process that needs to be tailored to each individual. Below are proposed phases of recovery:

Phase 1: Initial Conditioning

Goal: Improve dysfunctional breathing and build a basic aerobic capacity.

Method

  – Daily breath work focusing on diaphragmatic breathing for 5-20 minutes.

  – Light aerobic activities like walking or light cycling, maintaining a low intensity.

  – Isometric exercises to build foundational strength.

  – Stretching and mobility exercises for the rib cage and diaphragm.

  – Progressive muscle relaxation to reduce stress and improve mind-body connection.

Phase 2: Capacity Building

Goal: Enhance overall physical capacity, include respiratory muscle training.

Method:

  – Increase intensity of aerobic exercises while maintaining nasal breathing.

  – Transition to dynamic strength training.

  – Implement moderate-intensity respiratory muscle training.

  – Introduce red light therapy to enhance mitochondrial function and reduce inflammation.

Phase 3: Advanced Training

Goal: Further improve physical capabilities and integrate respiratory training.

Method

  – Push aerobic exercises to a higher intensity, but ensure it remains manageable.

  – Move to intermediate strength training routines.

  – Maintain respiratory muscle training at a higher intensity.

  – Continue red light therapy sessions for maintenance.

Phase 4: Specialized Training

Goal: Tailor the rehabilitation to specific goals, whether athletic or lifestyle-related.

Method

  – General and specific drills aligned to the individual’s goals.

  – Increase intensity and specificity of the training regimen.

 

Additional Considerations

Hydration: Electrolyte balance is crucial. Adding a pinch of salt to water can help.

Diet: Incorporate anti-inflammatory and antioxidant-rich foods to aid recovery.

Self-awareness and Journaling: Track symptoms and progress to avoid overexertion and manage expectations.

Involvement of Friends and Family: Social support plays a critical role in recovery.

Optimising Sleep: Ensure good sleep hygiene to enhance recovery.

Conclusion

Long COVID presents a complex set of challenges, but with a comprehensive, phased approach to rehabilitation, individuals can make significant strides in their recovery. By understanding the underlying mechanisms and integrating tailored strategies, we can help those affected regain their health and quality of life.

Debugging and validating these approaches through ongoing research and clinical practice will be key to refining our methods and ensuring the best outcomes for patients. Understanding, patience, and a multi-disciplinary approach are crucial to conquering Long COVID.

Should you wish to learn more about how to learn how to support those in managing long COVID using the aforemention method you might want to consider checking out our six month intensive certification program at www.breathscience.com.au

Should you want to watch the full 90 minute lecture detailing all the comprehensive literature and lecture on managing long covid along with more than 30 others lessons in breath science you might want to check out our members area at www.schoolofbreathscience.com

References

Wagner, R. R. and Krug, . Robert M. (2024, June 18). virus. Encyclopedia Britannica. https://www.britannica.com/science/virus

Tomohiro Sawa, Takaaki Akaike (2022) Viruses: What triggers inflammation in COVID-19? eLife 11:e76231 https://doi.org/

Cui, X., Chen, W., Zhou, H., Gong, Y., Zhu, B., Lv, X., … & Ma, H. (2021). Pulmonary edema in COVID-19 patients: mechanisms and treatment potential. Frontiers in pharmacology, 12, 664349.

van der Togt, V., & Rossman, J. S. (2023). Hypothesis: inflammatory acid-base disruption underpins Long Covid. Frontiers in Immunology, 14, 1150105.

Sick, J., & König, D. (2023). Exercise training in non-hospitalized patients with post-COVID-19 syndrome—a narrative review. In Healthcare (Vol. 11, No. 16, p. 2277). MDPI.

National Institute for Health and Care Excellence. (2020). COVID-19 rapid guideline: managing the long-term effects of COVID-19. National Institute for Health and Care Excellence.

Al-Aly, Z., & Topol, E. (2024). Solving the puzzle of Long Covid. Science, 383(6685), 830-832.

Chuang, H. J., Lin, C. W., Hsiao, M. Y., Wang, T. G., & Liang, H. W. (2024). Long COVID and rehabilitation. Journal of the Formosan Medical Association, 123, S61-S69.

Durstenfeld, M. S., Sun, K., Tahir, P., Peluso, M. J., Deeks, S. G., Aras, M. A., … & Hsue, P. Y. (2022). Use of cardiopulmonary exercise testing to evaluate long COVID-19 symptoms in adults: a systematic review and meta-analysis. JAMA network open, 5(10), e2236057-e2236057.

Singh I, Joseph P, Heerdt PM, Cullinan M, Lutchmansingh DD, Gulati M, Possick JD, Systrom DM, Waxman AB. Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing. Chest. 2022 Jan;161(1):54-63. doi: 10.1016/j.chest.2021.08.010. Epub 2021 Aug 11. PMID: 34389297; PMCID: PMC8354807.

Schwendinger, F., Knaier, R., Radtke, T., & Schmidt-Trucksäss, A. (2023). Low cardiorespiratory fitness post-COVID-19: a narrative review. Sports Medicine, 53(1), 51-74.

Szekely Y, Lichter Y, Sadon S, Lupu L, Taieb P, Banai A, Sapir O, Granot Y, Hochstadt A, Friedman S, Laufer-Perl M, Banai S, Topilsky Y. Cardiorespiratory Abnormalities in Patients Recovering from Coronavirus Disease 2019. J Am Soc Echocardiogr. 2021 Dec;34(12):1273-1284.e9. doi: 10.1016/j.echo.2021.08.022. Epub 2021 Sep 8. PMID: 34508837; PMCID: PMC8425293.

Schwendinger, F., et al. “COVID-19 sequelae and exercise capacity: a systematic review.” Sports Medicine (2021).

Zhang, S., Bai, W., Yue, J. et al. Eight months follow-up study on pulmonary function, lung radiographic, and related physiological characteristics in COVID-19 survivors. Sci Rep 11, 13854 (2021). https://doi.org/10.1038/s41598-021-93191-y

Dani, M., Dirksen, A., Taraborrelli, P., Torocastro, M., Panagopoulos, D., Sutton, R., & Lim, P. B. (2021). Autonomic dysfunction in ‘long COVID’: rationale, physiology and management strategies. Clinical Medicine, 21(1), e63-e67.

Chuang, H. J., Lin, C. W., Hsiao, M. Y., Wang, T. G., & Liang, H. W. (2024). Long COVID and rehabilitation. Journal of the Formosan Medical Association, 123, S61-S69.

Schutz, A., & Luckmann, T. (1973). The structures of the life-world. Northwestern University Press.

Fang, C., Baz, S. A., Sheard, L., & Carpentieri, J. D. (2024). ‘I am just a shadow of who I used to be’—Exploring existential loss of identity among people living with chronic conditions of Long COVID. Sociology of Health & Illness, 46(1), 59-77.

Fan, J., Chang, Y., Cheng, S. et al. Effect of breathing exercises on patients with interstitial lung disease: A systematic review and meta-analysis. Qual Life Res (2024). https://doi.org/10.1007/s11136-024-03679-z

Melendez-Oliva, E., Martínez-Pozas, O., Cuenca-Zaldivar, J. N., Villafañe, J. H., Jimenez-Ortega, L., & Sanchez-Romero, E. A. (2023). Efficacy of pulmonary rehabilitation in post-COVID-19: a systematic review and meta-analysis. Biomedicines, 11(8), 2213.

Jimeno-Almazán, A., Buendía-Romero, Á., Martínez-Cava, A., Franco-López, F., Sánchez-Alcaraz, B. J., Courel-Ibáñez, J., & Pallarés, J. G. (2023). Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations on recovery from post-COVID-19 conditions: the RECOVE trial. Journal of Applied Physiology, 134(1), 95-104.

Ao, J., Wood, J. P., Chidlow, G., Gillies, M. C., & Casson, R. J. (2018). Retinal pigment epithelium in the pathogenesis of age‐related macular degeneration and photobiomodulation as a potential therapy?. Clinical & experimental ophthalmology, 46(6), 670-686.

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